Blar i NTNU Open på forfatter "Pawel, Mielnik"

Viser treff 1-5 av 5

    • Discontinuation rate of sulfasalazine, leflunomide and methotrexate due to adverse events in a real-life setting (NOR-DMARD) 

      Pawel, Mielnik; Sexton, Joseph; Fagerli, Karen Minde; Bakland, Gunnstein; Hu, Yi; Kristianslund, Eirik; Hoff, Mari; Wierød, Ada; Kvien, Tore Kristian Aaserud (Peer reviewed; Journal article, 2023)
      Objectives MTX, LEF and SSZ are conventional synthetic DMARDs (csDMARDs) with a well-established role in the treatment of RA. We aimed to estimate and compare the relative risks for adverse events (AEs) and the ...

    • Effect of Therapeutic Drug Monitoring vs Standard Therapy During Infliximab Induction on Disease Remission in Patients With Chronic Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial 

      Syversen, Silje Watterdal; Goll, Guro Løvik; Jørgensen, Kristin Kaasen; Sandanger, Øystein; Sexton, Joseph; Olsen, Inge Christoffer; Gehin, Johanna Elin; Warren, David; Brun, Marthe Kirkesæther; Klaasen, Rolf; Karlsen, Lars Normann; Noraberg, Geir; Zettel, Camilla; Ljoså, Maud-Kristine Aga; Haugen, Anne Julsrud; Njålla, Rune Johan; Bruun, Trude J; Seeberg, Kathrine; Michelsen, Brigitte; Strand, Eldri Kveine; Skorpe, Svanaug; Blomgren, Ingrid; Bragnes, Yngvill; Dotterud, Christian; Thune, Turid Jorunn; Ystrøm, Carl Magnus; Torp, Roald; Pawel, Mielnik; Mørk, Cato; Kvien, Tore Kristian; Jahnsen, Jørgen; Bolstad, Nils; Haavardsholm, Espen A. (Peer reviewed; Journal article, 2021)
      Importance: Proactive therapeutic drug monitoring (TDM), defined as individualized drug dosing based on scheduled monitoring of serum drug levels, has been proposed as an alternative to standard therapy to maximize efficacy ...

    • Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial 

      Barratt-Due, Andreas; Olsen, Inge Christoffer; Nezvalova-Henriksen, Katerina; Kåsine, Trine; Lund-Johansen, Fridtjof; Hoel, Hedda Benedicte; Holten, Aleksander Rygh; Tveita, Anders Aune; Mathiessen, Alexander; Haugli, Mette; Eiken, Ragnhild; Kildal, Anders Benjamin; Berg, Åse; Johannessen, Asgeir; Heggelund, Lars; Dahl, Tuva Børresdatter; Skåra, Karoline Hansen; Pawel, Mielnik; Le, Lan Ai Kieu; Thoresen, Lars; Ernst, Gernot; Hoff, Dag Arne Lihaug; Skudal, Hilde Kristin; Kittang, Bård Reiakvam; Olsen, Roy Bjørkholt; Tholin, Birgitte; Ystrøm, Carl Magnus; Skei, Nina Vibeche; Tran, Trung; Dudman, Susanne Gjeruldsen; Andersen, Jan Terje; Hannula, Raisa; Dalgard, Olav; Finbråten, Ane-Kristine; Tonby, Kristian; Blomberg, Bjørn; Aballi, Saad; Fladeby, Cathrine; Steffensen, Anne Katrine; Müller, Fredrik; Dyrhol-Riise, Anne Ma; Trøseid, Marius; Aukrust, Pål (Peer reviewed; Journal article, 2021)
      Background: New treatment modalities are urgently needed for patients with COVID-19. The World Health Organization (WHO) Solidarity trial showed no effect of remdesivir or hydroxychloroquine (HCQ) on mortality, but the ...

    • Exploring drug cost and disease outcome in rheumatoid arthritis patients treated with biologic and targeted synthetic DMARDs in Norway in 2010–2019 – a country with a national tender system for prescription of costly drugs 

      Brkic, Alen; Diamantopoulos, Andreas P; Haavardsholm, Espen A.; Fevang, Bjørg Tilde Svanes; Brekke, Lene Kristin; Loli, Liz Paucar; Zettel, Camilla; Rødevand, Erik; Bakland, Gunnstein; Pawel, Mielnik; Haugeberg, Glenn (Peer reviewed; Journal article, 2022)
      Background In Norway, an annual tender system for the prescription of biologic and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) has been used since 2007. This study aimed to explore annual ...

    • Exploring the impact of the national tender system on the use of costly drugs treating rheumatoid arthritis patients in ten rheumatology centers in Norway (2010–2019) 

      Brkic, Alen; Diamantopoulos, Andreas P; Hoff, Mari; Haavardsholm, Espen A.; Fevang, Bjørg Tilde Svanes; Brekke, Lene Kristin; Loli, Liz Paucar; Zettel, Camilla; Bakland, Gunnstein; Pawel, Mielnik; Haugeberg, Glenn (Peer reviewed; Journal article, 2023)
      Background Biologic and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) are highly effective in treating rheumatoid arthritis (RA), albeit high drug cost has restricted their use in many countries. ...